I have had two company cars, a Chevy Malibu and a Ford Fusion. The Ford was 10 times the car the Chevy was, no issues in 60,000 miles where the Chevy was in the shop 6 times. Both were V-6's.
My company went to 4 cyls and while I don't mind a 4cyl a 4cyl domestic is out of the question. For that and other reasons I am driving a Toyota Camry that I bought in the middle of August. I already have 15,000 miles on it and I love it. Averaging 27.94 MPG so far, with a best tank of 31.7 MPG not bad for a V-6 with 260+ HP.
My point here, is I needed a car that I could drive 250,000 miles over the next 5 years and the only cars that were on my list were the Honda and the Toyota.
I have always bought domestics in the past, selling my wifes 5 year old Civic (she paid 14,000 new) with 70,000 miles for $8500 got me to look at Honda / Toyotas.
For the money I would stick with Honda or Toyota
1) Toyota
2) Honda
3) Nissan, Subaru
4) Mazda and the the better Domestics
5) Hyundai and the worse Domestics
6) Kia and Suzuki